ARMGO Pharma, Inc., is a privately held biopharmaceutical company dedicated to applying targeted mechanism-based science to the development of novel small-molecule therapeutics to treat cardiac, musculoskeletal, and neurological disorders characterized by leaky Ryanodine Receptor (RyR) calcium channels. Leaky RyRs are caused by genetic mutations as well as post-translational modifications of RyR channels. The company's proprietary drugs, known as Rycals®, are a new class of oral agents that repair calcium leaks through the RyR. ARMGO Pharma has been awarded an exclusive, worldwide license from Columbia University for its RyR technology based on the research of founding scientist Andrew R. Marks, M.D. The ARM210 program is supported through a Bench to Bedside grant from the NIH (NNS19005001), and a research collaboration and financial support from Les Laboratoires Servier.
