TScan designs therapies that reprogram a patient’s own T cells to recognize and fight their cancer using naturally-occurring TCRs that find and destroy shared cancer targets. The TScan technology process allows TCRs to be scanned against target antigens in a genome-wide, high-throughput, and unbiased fashion. TScan is developing a portfolio of TCR therapies for patients suffering from both liquid and solid tumors, and has already discovered, through this process, novel antigens from TCRs, novel TCRs from known antigens, and previously uncharacterized off-targets of known TCRs.
