Abcentra is a clinical-stage biopharmaceutical company developing first-in-class therapeutic antibodies to treat cardiovascular inflammation by blocking oxidized LDL. Oxidized LDL is a pro-inflammatory mediator that is strongly implicated in atherosclerotic cardiovascular disease, type 2 diabetes, calcific aortic valve disease and several inflammatory diseases (including psoriasis). Oxidized LDL blockade offers a promising new way to treat cardiovascular inflammation, which drives major cardiovascular events and affects millions of people in the United States.
Abcentra’s development pipeline consists of potential therapeutics for individuals with significant residual risk for a major cardiovascular event from chronic inflammation, including those with psoriasis, rheumatoid arthritis, and systemic lupus erythematosus.
